Date of Award

6-7-2016

Document Type

Thesis

Publisher

Santa Clara : Santa Clara University, 2016.

Department

Bioengineering

First Advisor

Kim, Unyoung

Abstract

For our study of Microfluidic Detection of Biogenic Amines, we have designed a microfluidic device to separate and detect different biogenic amine concentrations using amperometric detection. The goal of this project is to identify and quantify biogenic amines form the neural fluid extracted from the pericardial cavity of the Jonah crabs (Cancer Borealis). The device that we designed utilizes polydimethylsiloxane (commonly known as PDMS) along with a carbon paste electrode and a palladium decoupler. Using capillary electrophoresis (CE) along with amperometric detection, we aim to separate biogenic amines and detect them with amperometric detection.

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