Date of Award

6-4-2015

Document Type

Thesis - SCU Access Only

Publisher

Santa Clara University

First Advisor

Zhiwen Zhang

Abstract

Our project, Biological Applications of Scanning Thermal Microscopy, is a partnership between Applied Nanostructures and Santa Clara University students Warren Jolley and Amanda Brantner. The goal is to demonstrate the novel applications of the Vertisense™ thermal atomic force microscope probe, developed by AppNano with regards to biological materials. Gold and Silver nanoand microparticles were imaged, as well as spider silk and carbon nanotube/epoxy test samples. We demonstrated that the Vertisense™ probe is capable of imaging unique thermal characteristics regardless of topography by means of captured spider silk, and developed a process to immobilize and scan other kinds of substances with greater ease in the future. We believe that the results of our project can lead to improved methods of imaging in medicine and cell biology.

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