Logan Thomsen

Date of Award

2023

Document Type

Thesis - SCU Access Only

Publisher

Santa Clara : Santa Clara University, 2023.

Department

Bioengineering

First Advisor

Emre Araci

Second Advisor

Maryam Mobed-Miremadi

Abstract

Microfluidics is the scientific field that uses microscopic channels to manipulate liquids measuring between 10-3 and 10-10 liters, though usually quantified in the μL scale. These systems are utilized for biochemical sensors and tests that are referred to in literature and popular science as several names, including biochips. A microfluidic system can be analyzed by its fabrication method or materials. Consumer applications of microfluidics include paper tests, and academic research has focused on glass engraving.

The Minilab project is aimed at establishing a biochip fabrication method with a pattern of channels for fluid testing. The selected process uses three microfluidic fabrication concepts: xurography on copper sheet metal, using a transfer stamp, and then embossing on a hydro gel mixture. Fluid flow in the biochips was unsuccessful, but there is potential for the Minilab fabrication process to provide an adaptive, affordable, and environmentally friendly alternative to other fabrication methods. In the future, this system could be applied in consumer markets like education, at home testing, and applications in remote locations.


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