Simulation and verification of macroscopic isotropy of hollow alginate-based microfibers
Document Type
Article
Publication Date
4-1-2014
Publisher
Taylor & Francis
Abstract
A simulation of tensile strength of various alginate-based hollow microfibers using FEA analysis has been conducted with the hypothesis of macroscopic isotropy and linear elastic-plastic behavior. Results of student t-tests indicated that there was no significant difference between the experimental and simulated tensile strengths (p = 0.37, α = 0.05), while there was a significant reduction in elasticity as a result of chitosan coating (p = 0.024, α = 0.05). The hypothesis of macroscopic isotropy was verified by highly correlated (R2 ≥ 0.92) theoretical and experimental elongation at break measurements, findings that could be extended to the failure analysis of alginate microfibers used in regenerative medicine.
Recommended Citation
Djomehri, S., Zeid, H., Yavari, A., Mobed-Miremadi, M., Youssefi, K., & Liao-Chan, S. (2015). Simulation and verification of macroscopic isotropy of hollow alginate-based microfibers. Artificial Cells, Nanomedicine, and Biotechnology, 43(6), 390–397. https://doi.org/10.3109/21691401.2014.897629