Microfluidic gel arrays for the study of enzymatic activity

Document Type

Conference Proceeding

Publication Date

10-2014

Publisher

International Conference on Miniaturized Systems for Chemistry and Life Sciences

Abstract

We present a novel and flexible gel array platform to study enzymatic activity in confined environments. Recent research has highlighted the importance of studying proteins in confined environments that replicate the inside of cells rather than studying proteins in dilute solutions. Our platform allows the punctual and selective introduction of substrates and the quantitative readout of product formation to study the effect of protein confinement on enzymatic activity.

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