Date of Award

Spring 2019

Document Type

Thesis - SCU Access Only


Santa Clara : Santa Clara University, 2019



First Advisor

Zhiwen Zhang


Pancreatic cancer is expected to be the second leading cause of cancer-related deaths by 2030, mainly because early detection is so difficult. The most common biomarker, CA 19-9, for pancreatic cancer has a low success rate for early detection. We aim to incorporate the unnatural amino acid L-DOPA in a peptide to increase the binding affinity between the protein and CA 19-9. Our results will show that a protein-sugar interaction can occur, which would expand the capabilities for other disease diagnostics.

SCU Access Only

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