Simulation and verification of macroscopic isotropy of hollow alginate-based microfibers
Taylor & Francis
A simulation of tensile strength of various alginate-based hollow microfibers using FEA analysis has been conducted with the hypothesis of macroscopic isotropy and linear elastic-plastic behavior. Results of student t-tests indicated that there was no significant difference between the experimental and simulated tensile strengths (p = 0.37, α = 0.05), while there was a significant reduction in elasticity as a result of chitosan coating (p = 0.024, α = 0.05). The hypothesis of macroscopic isotropy was verified by highly correlated (R2 ≥ 0.92) theoretical and experimental elongation at break measurements, findings that could be extended to the failure analysis of alginate microfibers used in regenerative medicine.
Djomehri, S., Zeid, H., Yavari, A., Mobed-Miremadi, M., Youssefi, K., & Liao-Chan, S. (2015). Simulation and verification of macroscopic isotropy of hollow alginate-based microfibers. Artificial Cells, Nanomedicine, and Biotechnology, 43(6), 390–397. https://doi.org/10.3109/21691401.2014.897629