Microfluidic gel arrays for the study of enzymatic activity
International Conference on Miniaturized Systems for Chemistry and Life Sciences
We present a novel and flexible gel array platform to study enzymatic activity in confined environments. Recent research has highlighted the importance of studying proteins in confined environments that replicate the inside of cells rather than studying proteins in dilute solutions. Our platform allows the punctual and selective introduction of substrates and the quantitative readout of product formation to study the effect of protein confinement on enzymatic activity.
Sowash, C.; Smith, C.; Tullis, J.; Kunkel, J.; Asuri, P.; Abbyad, P. Microfluidic gel arrays for the study of enzymatic activity, Proceedings of MicroTAS Conference, W.249b (2014).